Article
Genetic variation in VTCN1 (B7-H4) is associated with course of disease in juvenile idiopathic arthritis.
Annals of the rheumatic diseases - 1 Jun 2014
Albers H M, Reinards T H C M, Brinkman D M C, Kamphuis S S M, van Rossum M A J, Hoppenreijs E P A H, Girschick H J, Wouters C, Saurenmann R K, Bakker E, Verduijn W, Slagboom P, Huizinga T W J, Toes R E M, Houwing-Duistermaat J J, ten Cate R, Schilham M W
Abstract excerpt
OBJECTIVE: The course of disease in juvenile idiopathic arthritis (JIA) is unpredictable with episodes of activity and remission. In order to identify predictive factors, 93 SNPs, JIA subtype, age at onset and ANA status were studied in relation to disease course. METHODS: Genetic and clinical parameters were analysed in a cohort of 272 Caucasian patients with persistent oligoarthritis (n=129), extended...
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