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Article

Novel genetic association of the VTCN1 region with rheumatoid arthritis.

Annals of the rheumatic diseases - 1 Apr 2012

Daha Nina A, Lie Benedicte A, Trouw L A, Stoeken Gerrie, Schonkeren Joris J M, Ding Bo, Kvien Tore K, Schilham Marco W, Padyukov Leonid, Huizinga T W J, Toes Rene

Abstract excerpt

OBJECTIVE: Based upon findings in juvenile idiopathic arthritis, the genetic contribution of the VTCN1 region to rheumatoid arthritis (RA) susceptibility and anticitrullinated protein antibody (ACPA) status was investigated. VTCN1 is known to play a pivotal role in regulation of the immune system and, in soluble form, has previously been associated with higher disease activity. METHODS: Ten VTCN1 polymorphisms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22323440
DOI: 10.1136/annrheumdis-2011-200574

Genes

VTCN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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