Article
Heritability and genetic association analysis of cognition in the Diabetes Heart Study.
Neurobiology of aging - 1 Aug 2014
Cox Amanda J, Hugenschmidt Christina E, Raffield Laura M, Langefeld Carl D, Freedman Barry I, Williamson Jeff D, Hsu Fang-Chi, Bowden Donald W
Abstract excerpt
Cognitive performance is an important component of healthy aging. Type 2 diabetes (T2D) is associated with negative outcomes for the brain and cognition, although causal mechanisms have not been definitely determined. Genetic risk factors warrant further consideration in this context. This study examined the heritability of cognitive function as assessed by (1) the Digit Symbol Substitution Task; (2) the Modified...
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