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Article

SuperBiHelix method for predicting the pleiotropic ensemble of G-protein-coupled receptor conformations.

Proceedings of the National Academy of Sciences of the United States of America - 7 Jan 2014

Bray Jenelle K, Abrol Ravinder, Goddard William A, Trzaskowski Bartosz, Scott Caitlin E

Abstract excerpt

There is overwhelming evidence that G-protein-coupled receptors (GPCRs) exhibit several distinct low-energy conformations, each of which might favor binding to different ligands and/or lead to different downstream functions. Understanding the function of such proteins requires knowledge of the en...

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Identifiers

PMID: 24344284
DOI: 10.1073/pnas.1321233111
PMCID: PMC3890820

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24344284-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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