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Article

The 5-HTTLPR genotype modulates heart rate variability and its adjustment by pharmacological panic challenge in healthy men.

Journal of psychiatric research - 1 Mar 2014

Agorastos Agorastos, Kellner Michael, Stiedl Oliver, Muhtz Christoph, Becktepe Jos S, Wiedemann Klaus, Demiralay Cüneyt

Abstract excerpt

Abnormal serotonin transporter (5-HTT) function and autonomic nervous system (ANS) dysregulation has been proposed in panic disorder. However, in contrast to hypothalamo-pituitary-adrenocortical (HPA) functioning, ANS reactivity during panic response has yet not been investigated in humans with respect to the 5-HTT genotype. The present study assessed the influence of challenging by cholecystokinin tetrapeptide...

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Source

Identifiers

PMID: 24342768
DOI: 10.1016/j.jpsychires.2013.11.013

Genes

CCK
HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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