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Article

The symptomatic profile of panic disorder is shaped by the 5-HTTLPR polymorphism.

Progress in neuro-psychopharmacology & biological psychiatry - 13 Nov 2009

Lonsdorf Tina B, Rück Christian, Bergström Jan, Andersson Gerhard, Ohman Arne, Schalling Martin, Lindefors Nils

Abstract excerpt

The short allele of a functional polymorphism (5-HTTLPR) in the serotonin transporter (5-HTT) promoter is associated with reduced serotonin transporter expression, lower in vivo 5-HTT binding, higher neuroticism and amygdala reactivity as well as facilitated fear conditioning and is a candidate v...

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Source

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PMID: 19683026
DOI: 10.1016/j.pnpbp.2009.08.004

Genes

HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19683026-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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