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Mutational analysis of the BRCA2 gene in breast carcinoma patients of Kashmiri descent.

Molecular medicine reports - 1 Feb 2014

Ayub Shiekh Gazalla, Rasool Shabhat, Ayub Taha, Khan Saquib Naveed, Wani Khursheed Alam, Andrabi Khurshid Iqbal

Abstract excerpt

Breast cancer demonstrates geographical and ethnic variation in its incidence reflecting the effect of local environmental conditions and lifestyle. The genesis of the disease has further been complexed by the involvement of a number of genes with small effects and above all by population heterogeneity. Accordingly, variations in genes, including breast cancer 1, early onset (BRCA1)/breast cancer 2, early onset...

Topics

Aged
BRCA2 Protein
Breast Neoplasms
DNA Mutational Analysis
Female
Genetic Association Studies
Genetic Predisposition to Disease
Humans
India
Middle Aged
Mutation, Missense

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24337145
DOI: 10.3892/mmr.2013.1862

Genes

BRCA2
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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