Article
Mutational analysis of the BRCA2 gene in breast carcinoma patients of Kashmiri descent.
Molecular medicine reports - 1 Feb 2014
Ayub Shiekh Gazalla, Rasool Shabhat, Ayub Taha, Khan Saquib Naveed, Wani Khursheed Alam, Andrabi Khurshid Iqbal
Abstract excerpt
Breast cancer demonstrates geographical and ethnic variation in its incidence reflecting the effect of local environmental conditions and lifestyle. The genesis of the disease has further been complexed by the involvement of a number of genes with small effects and above all by population heterogeneity. Accordingly, variations in genes, including breast cancer 1, early onset (BRCA1)/breast cancer 2, early onset...
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