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Article

Low incidence of BRCA2 mutations in breast carcinoma and other cancers.

Nature genetics - 1 Jun 1996

Teng D H, Bogden R, Mitchell J, Baumgard M, Bell R, Berry S, Davis T, Ha P C, Kehrer R, Jammulapati S, Chen Q, Offit K, Skolnick M H, Tavtigian S V, Jhanwar S, Swedlund B, Wong A K, Kamb A

Abstract excerpt

Inherited mutant alleles of familial tumour suppressor genes predispose individuals to particular types of cancer. In addition to an involvement in inherited susceptibility to cancer, these tumour suppressor genes are targets for somatic mutations in sporadic cancers of the same type found in the...

Topics

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Mutation
Molecular Sequence Data
Base Sequence
Polymerase Chain Reaction
Heterozygote

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tumor Cells, Cultured

Sequence Analysis, DNA

Transcription Factors

Source

Identifiers

PMID: 8640236
DOI: 10.1038/ng0696-241

Genes

BRCA2
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-8640236-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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