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Article

Novel germline mutations in BRCA2 gene among 96 hereditary breast and breast-ovarian cancer families from Kerala, South India.

Journal of cancer research and clinical oncology - 1 Nov 2007

Syamala Vani, Sreeja Leelakumari, Syamala Volga S, Vinodkumar B, Raveendran Praveenkumar B, Sreedharan Hariharan, Kuttappan Ratheesan, Balakrishnan Lekshmi, Ankathil Ravindran

Abstract excerpt

PURPOSE: Aim of the present study was to identify the genetic heterogeneity, prevalence and frequency of germline mutations of BRCA2 gene in Hereditary Breast/Ovarian cancer patients from Kerala, South India. METHODS: We analyzed 102 Breast/Ovarian cancer patients from 96 breast and/ovarian cancer families for BRCA2 gene mutations using Conformation-Sensitive Gel Electrophoresis (CSGE) followed by sequencing....

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Identifiers

PMID: 17503080
DOI: 10.1007/s00432-007-0229-6

Genes

BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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