Article
Inversed relationship between CD44 variant and c-Myc due to oxidative stress-induced canonical Wnt activation.
Biochemical and biophysical research communications - 10 Jan 2014
Yoshida Go J, Saya Hideyuki
Abstract excerpt
Cancer stem-like cells express high amount of CD44 variant8-10 which protects cancer cells from redox stress. We have demonstrated by immunohistochemical analysis and Western blotting, and reverse-transcription polymerase chain reaction, that CD44 variant8-10 and c-Myc tend to show the inversed expression manner in gastric cancer cells. That is attributable to the oxidative stress-induced canonical Wnt...
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