Article
The association of FOXO3A gene polymorphisms with serum FOXO3A levels and oxidative stress markers in vitiligo patients.
Gene - 15 Feb 2014
Ozel Turkcu Ummuhani, Solak Tekin Nilgun, Gokdogan Edgunlu Tuba, Karakas Celik Sevim, Oner Setenay
Abstract excerpt
Vitiligo is an acquired epidermal pigment loss of the skin. Oxidative stress is one of the major theories in the pathophysiology of vitiligo. FOXO3A is the forkhead members of the class O (FOXO) transcription factors, and plays an important role in cell cycle regulation, apoptosis, oxidative stress, and DNA repair. The aim of our study was to investigate FOXO3A gene polymorphisms and FOXO3A protein levels,...
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