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The susceptibility to vitiligo is associated with NF‐E2‐related factor2 (<i>Nrf2</i>) gene polymorphisms: a study on Chinese Han population

4 Jun 2008

Abstract excerpt

Vitiligo is an acquired pigmentary disorder and its pathogenesis remains unclear. Oxidative stress is considered to be the initial pathogenic event in the melanocyte destruction. NF-E2-related factor2 (Nrf2) is a transcription factor regulating the expression of detoxifying and antioxidant genes. To investigate the association of the Nrf2 gene promoter polymorphisms with vitiligo in Chinese Han population, the...

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PMID: 18537816
DOI: 10.1111/j.1600-0625.2008.00752.x

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