Article
Heterogeneity of Paucigranulocytic Asthma: A Prospective Cohort Study with Hierarchical Cluster Analysis.
The journal of allergy and clinical immunology. In practice - 1 Jun 2021
Deng Ke, Zhang Xin, Liu Ying, Zhang Li, Wang Gang, Feng Min, Oliver Brian G, Wang Lei, Hansbro Philip M, Qin Lin, Xie Min, Chen Zhi Hong, Simpson Jodie, Zhang Jie, Li Wei Min, Wang Gang, Gibson Peter Gerard
Abstract excerpt
BACKGROUND: Asthma, a heterogeneous disease, can be divided into 4 inflammatory phenotypes using induced sputum cell counts-eosinophilic asthma (EA), neutrophilic asthma (NA), mixed granulocytic asthma, and paucigranulocytic asthma (PGA). Although research has focused on EA and NA, there is little known about PGA. OBJECTIVE: To study the heterogeneity of PGA and identify possible PGA clusters to guide clinical...
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