Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The ocular surface phenotype of Muc5ac and Muc5b null mice.

Investigative ophthalmology & visual science - 15 Jan 2014

Marko Christina Kaiser, Tisdale Ann S, Spurr-Michaud Sandra, Evans Christopher, Gipson Ilene K

Abstract excerpt

PURPOSE: Recent development of mice null for either Muc5ac or Muc5b mucin allows study of their specific roles at the mouse ocular surface. A recent report indicated that Muc5ac null mice show an ocular surface phenotype similar to that seen in dry eye syndrome. The purpose of our study was to de...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mucin-5B
Share to Conjunctiva
Share to Cornea

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Mice, Inbred C57BL

Share to Microscopy, Fluorescence

Share to Mucin 5AC

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 24327612
DOI: 10.1167/iovs.13-13194
PMCID: PMC3894795

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24327612-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The ocular surface phenotype of Muc5ac and Muc5b null mice.PMID 24327612Read ↗

Mucin deficiency causes functional and structural changes of the ocular surface.Semantic proximity Read ↗

Ocular surface mucins and local inflammation—studies in genetically modified mouse linesSemantic proximity Read ↗

C57BL/6 mice lacking Muc1 show no ocular surface phenotype.Semantic proximity Read ↗

What We Have Learned From Animal Models of Dry EyeSemantic proximity Read ↗

Macrophage Phenotype in the Ocular Surface of Experimental Murine Dry Eye Disease.Semantic proximity Read ↗

Effects of the loss of conjunctival Muc16 on corneal epithelium and stroma in mice.Semantic proximity Read ↗

Membrane-associated mucins of the ocular surface: New genes, new protein functions and new biological roles in human and mouseSemantic proximity Read ↗

Clusterin Seals the Ocular Surface Barrier in Mouse Dry EyeSemantic proximity Read ↗

A Novel C-Terminal Mutation in Gsdma3 (C+/H-) Leads to Alopecia and Corneal Inflammatory Response in Mice.Semantic proximity Read ↗

Physiological effects of inactivation and the roles of Elovl3/ELOVL3 in maintaining ocular homeostasis.Semantic proximity Read ↗

Spdef null mice lack conjunctival goblet cells and provide a model of dry eye.Semantic proximity Read ↗

Circadian disruption reduces MUC4 expression via clock molecule BMAL1 during dry eye developmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.