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Article

MmpL3 a potential new target for development of novel anti-tuberculosis drugs

11 Dec 2013

Abstract excerpt

INTRODUCTION: Tuberculosis (TB) is still a leading cause of mortality in the developing world and there is an unmet clinical need for new drugs with novel mechanism of action. Targeting the complex and unique cell wall of TB-causing pathogen Mycobacterium tuberculosis (Mtb) has been a mainstay of TB drug discovery. Though, the composition of the cell wall of Mtb is well understood, little is known about the...

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PMID: 24325728
DOI: 10.1517/14728222.2014.859677

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