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Article

Promoter methylation and genetic polymorphism of glutathione S-transferase P1 gene (GSTP1) in Thai breast- cancer patients.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2011

Pongtheerat Tanett, Pakdeethai Supparit, Purisa Wichai, Chariyalertsak Sunanta, Petmitr Songsak

Abstract excerpt

The GSTP1 gene encodes for a detoxification enzyme involved in protecting cells from carcinogens. In breast cancer, GSTP1 polymorphisms may produce lower effective enzyme detoxification properties and GSTP1 promoter hypermethylation may result in inactivation of GSTP1 expression. We therefore hypothesized an influence on progression of breast cancer. To study the effect of GSTP1 polymorphisms and CpG-island...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22320983

Genes

GSTP1

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Promoter methylation and genetic polymorphism of glutathione S-transferase P1 gene (GSTP1) in Thai breast- cancer patients.PMID 22320983Read ↗

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