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Article

Pharmacogenomics of acute lymphoid leukemia: new insights into treatment toxicity and efficacy.

Hematology. American Society of Hematology. Education Program - 1 Jan 2013

Relling Mary V, Ramsey Laura B

Abstract excerpt

Childhood acute lymphoblastic leukemia (ALL) provides an outstanding model for pharmacogenomic research: it is a drug-responsive disseminated cancer that is cured with medications alone in ∼ 85% of patients, but relapse remains unacceptably high for some subgroups. Inherited genomic variation contributes to the risk of relapse and to the risk of short- and long-term serious adverse effects of therapy. Our goal is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24319173
DOI: 10.1182/asheducation-2013.1.126

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