Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Resequencing the APOE gene reveals that rare mutations are not significant contributory factors in the development of type III hyperlipidemia.

Journal of clinical lipidology - 1 Jan 2000

Evans David, Beil Frank Ulrich, Aberle Jens

Abstract excerpt

BACKGROUND: APOE (apolipoprotein E gene) 2/2 genotype and an apolipoprotein B/total cholesterol (ApoB/TC) ratio <0.15 are diagnostic for type III hyperlipidemia. We hypothesized that patients with APOE genotype 2/3 or 2/4 and an ApoB/TC ratio <0.15 may have a mutation in their epsilon 3 or 4 alle...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Apolipoproteins B
Share to Apolipoproteins E

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Hyperlipoproteinemia Type III

Share to Sequence Analysis, DNA

Share to Triglycerides

Source

Identifiers

PMID: 24314366
DOI: 10.1016/j.jacl.2013.05.003

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24314366-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Resequencing the APOE gene reveals that rare mutations are not significant contributory factors in the development of type III hyperlipidemia.PMID 24314366Read ↗

Contribution of APOE Genetic Variants to DyslipidemiaSemantic proximity Read ↗

Lipoprotein profiles in a family with two mutants of apolipoprotein E: possible association with hypertriglyceridaemia but not with dysbetalipoproteinaemia.Semantic proximity Read ↗

The role of apolipoprotein E genetic variants in lipoprotein disorders.Semantic proximity Read ↗

Apolipoprotein E and familial dysbetalipoproteinemia: clinical, biochemical, and genetic aspects.Semantic proximity Read ↗

Genetic heterogeneity of apolipoprotein E and its influence on plasma lipid and lipoprotein levels.Semantic proximity Read ↗

Contribution of regulatory and structural variations in APOE to predicting dyslipidemia.Semantic proximity Read ↗

The p.Leu167del Mutation in APOE Gene Causes Autosomal Dominant Hypercholesterolemia by Down-regulation of LDL Receptor Expression in Hepatocytes.Semantic proximity Read ↗

Apolipoprotein E1 Baden (Arg(180)-->Cys). A new apolipoprotein E variant associated with hypertriglyceridemia.Semantic proximity Read ↗

Human apolipoprotein E: correlation of polymorphisms and serum lipid concentrations in Chinese.Semantic proximity Read ↗

Patients with apoE3 deficiency (E2/2, E3/2, and E4/2) who manifest with hyperlipidemia have increased frequency of an Asn 291-->Ser mutation in the human LPL gene.Semantic proximity Read ↗

The Apolipoprotein E2(Arg145Cys) Mutation Causes Autosomal Dominant Type III Hyperlipoproteinemia With Incomplete PenetranceSemantic proximity Read ↗

ApoB-48 and apoB-100 differentially influence the expression of type-III hyperlipoproteinemia in APOE*2 mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.