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Article

Fingolimod (FTY720) stimulates Ca(2+)/calcineurin signaling in fission yeast.

PloS one - 1 Jan 2013

Hagihara Kanako, Kita Ayako, Mizukura Aya, Yao Mariko, Kitai Yuki, Kunoh Tatsuki, Masuko Takashi, Matzno Sumio, Chiba Kenji, Sugiura Reiko

Abstract excerpt

Fingolimod hydrochloride (FTY720) is the first in class of sphingosine 1-phosphate (S1P) receptor modulator approved to treat multiple sclerosis via down-regulation of G protein-coupled S1P receptor 1 by its phosphorylated form (FTY720-P). Many studies have revealed that FTY720 exerts various bio...

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Identifiers

PMID: 24312601
DOI: 10.1371/journal.pone.0081907
PMCID: PMC3849299

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24312601-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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