Article
Using yeast to model calcium-related diseases: example of the Hailey-Hailey disease.
Biochimica et biophysica acta - 1 Oct 2014
Voisset Cécile, García-Rodríguez Néstor, Birkmire April, Blondel Marc, Wellinger Ralf Erik
Abstract excerpt
Cross-complementation studies offer the possibility to overcome limitations imposed by the inherent complexity of multicellular organisms in the study of human diseases, by taking advantage of simpler model organisms like the budding yeast Saccharomyces cerevisiae. This review deals with, (1) the use of S. cerevisiae as a model organism to study human diseases, (2) yeast-based screening systems for the detection...
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