Article
Frequent CCNE1 amplification in endometrial intraepithelial carcinoma and uterine serous carcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jul 2014
Kuhn Elisabetta, Bahadirli-Talbott Asli, Shih Ie-Ming
Abstract excerpt
Uterine serous carcinoma accounts for only 10% of all uterine epithelial cancers, but is the leading cause of death among them. The pathogenesis of this aggressive neoplasm has been largely elusive until recently, when comprehensive genome-wide analyses of uterine serous carcinoma have been performed. Among amplified cancer-related genes, CCNE1, encoding for cyclin E1, is frequently amplified in uterine serous...
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