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Gene amplification <i>CCNE1</i> is related to poor survival and potential therapeutic target in ovarian cancer

24 Mar 2010

Abstract excerpt

BACKGROUND: This study examined the clinical significance of CCNE1 (Cyclin E1) amplification and assessed whether CCNE1 is a potential therapeutic target in ovarian cancer. METHODS: CCNE1 expression and amplification in ovarian cancer was assessed by immunohistochemistry, fluorescence in situ hybridization and clinical data collected by retrospective chart review. CCNE1 gene knockdown using silencing RNA and a...

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PMID: 20336784
DOI: 10.1002/cncr.24987

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Gene amplification <i>CCNE1</i> is related to poor survival and potential therapeutic target in ovarian cancerPMID 20336784Read ↗

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