Article
Basic fibroblast growth factor is a key factor that induces bone marrow mesenchymal stem cells towards cells with Schwann cell phenotype.
Neuroscience letters - 24 Jan 2014
Zhu Hui, Yang Aizhen, Du Jinfeng, Li Donghui, Liu Mei, Ding Fei, Gu Xiaosong, Liu Yan
Abstract excerpt
Bone marrow mesenchymal stem cells (MSCs) can be differentiate towards a Schwann cells (SCs) lineage when exposed to pre-inducing reagents β-mercaptoethanol (BME) and retinoic acid (RA), followed by inducing factors: forskolin (FSK), basic fibroblast growth factor (bFGF), platelet derived growth factor (PDGF), and heregulin (HRG). However, the underlying mechanisms remain unclear. Here, we investigated the...
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