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Article

Human umbilical cord Wharton's jelly-derived mesenchymal stem cells differentiate into a Schwann-cell phenotype and promote neurite outgrowth in vitro.

Brain research bulletin - 28 Feb 2011

Peng Jiang, Wang Yu, Zhang Li, Zhao Bin, Zhao Zhe, Chen JiFeng, Guo QuanYi, Liu ShuYun, Sui Xiang, Xu WenJing, Lu ShiBi

Abstract excerpt

Cell-based therapy has achieved promising functional recovery for peripheral nerve repair. Although Schwann cells (SCs) and bone marrow derived mesenchymal stromal cells (BM-MSCs) are the main cell source for nerve tissue engineering, the clinical application is limited because of donor site morbidity, the invasive procedure, and the decreased number of SCs and BM-MSCs. Wharton's jelly-derived mesenchymal stem...

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Source

Identifiers

PMID: 21194558
DOI: 10.1016/j.brainresbull.2010.12.013

Genes

BDNF
MSC
NGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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