Article
Spontaneous expression of neural phenotype and NGF, TrkA, TrkB genes in marrow stromal cells.
Biochemical and biophysical research communications - 11 May 2007
Li Na, Yang Hui, Lu Lingling, Duan Chunli, Zhao Chunli, Zhao Huanying
Abstract excerpt
Marrow stromal cells (MSCs) have the ability to provide growth factors and differentiate into neural-like cells on treating with EGF, bFGF and other factors. We wanted to explore whether growth factors secreted by MSCs itself could induce self-differentiation into neural-like cells. Here, we show that even in the absence of inducing factors, rMSCs spontaneously differentiate into neural-like cells expressing...
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