Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of polymorphisms in LEPR with type 2 diabetes and related metabolic traits in a Chinese population.

Lipids in health and disease - 4 Jan 2018

Zhang Lulu, Qin Yingfen, Liang Danyan, Li Li, Liang Yaojie, Chen Lulin, Tong Lei, Zhou Jia, Li Hong, Zhang Haiying

Abstract excerpt

BACKGROUND: Leptin acts as a mediator of inflammation and energy homeostasis by activating leptin receptor (LEPR). We conducted this study to explore the association of polymorphisms in LEPR with type 2 diabetes mellitus (T2DM) and its related metabolic traits. METHODS: We performed a case-control study to investigate the association of polymorphisms in LEPR with T2DM and related metabolic traits in a Chinese...

Topics

Join the communities discussing this publication.

Asian People
Blood Glucose
Blood Pressure
Cholesterol, HDL
Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Expression

Receptors, Leptin

Source

Open in PubMed Open full text

Identifiers

PMID: 29301582
DOI: 10.1186/s12944-017-0644-x
PMCID: PMC5753482

Genes

LEPR
DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of polymorphisms in LEPR with type 2 diabetes and related metabolic traits in a Chinese population.PMID 29301582Read ↗

Variations in the Obesity Gene "LEPR" Contribute to Risk of Type 2 Diabetes Mellitus: Evidence from a Meta-Analysis.Semantic proximity Read ↗

Leptin Rs7799039 polymorphism is associated with type 2 diabetes mellitus Egyptian patients.Semantic proximity Read ↗

Genetic variations in the leptin and leptin receptor genes are associated with type 2 diabetes mellitus and metabolic traits in the Korean female population.Semantic proximity Read ↗

The association between leptin receptor gene polymorphisms and type 2 diabetes mellitus: A systematic review and meta-analysis.Semantic proximity Read ↗

Association analysis of polymorphisms in LEP (rs7799039 and rs2167270) and LEPR (rs1137101) gene towards the development of type 2 diabetes in North Indian Punjabi population.Semantic proximity Read ↗

Leptin receptor rs1137101 polymorphism and altered leptin-sOb-R axis contribute to type 2 diabetes risk in Gujarat population.Semantic proximity Read ↗

The haplotype identified in LEPR gene is associated with type 2 diabetes mellitus in Northern Chinese.Semantic proximity Read ↗

Association of leptin receptor gene polymorphisms and essential hypertension in a Chinese population.Semantic proximity Read ↗

Polymorphisms in the leptin receptor (LEPR)--putative association with obesity and T2DM.Semantic proximity Read ↗

Association of four insulin resistance genes with type 2 diabetes mellitus and hypertension in the Chinese Han population.Semantic proximity Read ↗

LEP rs7799039 and LEPR rs1137101 gene variants are not associated with clinical features in patients with metabolic syndrome in the Turkish population.Semantic proximity Read ↗

Genetic predisposition of LEPR (rs1137101) gene polymorphism related to type 2 diabetes mellitus - a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.