Article
The causal effect of red blood cell folate on genome-wide methylation in cord blood: a Mendelian randomization approach.
BMC bioinformatics - 4 Dec 2013
Binder Alexandra M, Michels Karin B
Abstract excerpt
BACKGROUND: Investigation of the biological mechanism by which folate acts to affect fetal development can inform appraisal of expected benefits and risk management. This research is ethically imperative given the ubiquity of folic acid fortified products in the US. Considering that folate is an essential component in the one-carbon metabolism pathway that provides methyl groups for DNA methylation, epigenetic...
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