Article
Sensory input is required for callosal axon targeting in the somatosensory cortex.
Molecular brain - 5 Dec 2013
Huang Ying, Song Ning-Ning, Lan Wei, Zhang Qiong, Zhang Ling, Zhang Lei, Hu Ling, Chen Jia-Yin, Zhao Chun-Jie, Li Lingjiang, Xu Lin, Ding Yu-Qiang
Abstract excerpt
BACKGROUND: Sensory input is generally thought to be necessary for refining and consolidating neuronal connections during brain development. We here report that cortical callosal axons in somatosensory cortex require sensory input for their target selection in contralateral cortex. RESULTS: Eliminating sensory input to either hemisphere by unilateral transection of infraorbital nerve (ION) prevents target...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.