Article
Association of novel single-nucleotide polymorphisms of the vascular endothelial growth factor-A gene with high-altitude adaptation in yak (Bos grunniens).
Genetics and molecular research : GMR - 18 Nov 2013
Wu X Y, Liang C N, Ding X Z, Guo X, Bao P J, Chu M, Liu W B, Yan P
Abstract excerpt
Vascular endothelial growth factor-A gene (VEGF-A) is a key regulator of angiogenesis and an endothelial cell mitogen that plays an important role in high-altitude adaptation. In this study, we detected 2 novel single-nucleotide polymorphisms (SNPs) of VEGF-A by screening for genetic variation in 700 individuals of 3 domestic Chinese yak breeds--namely Gannan (GN), Datong (DT), and Tianzhu white (TZW)--using...
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