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Article

VEGFA SNPs and transcriptional factor binding sites associated with high altitude sickness in Han and Tibetan Chinese at the Qinghai-Tibetan Plateau.

The journal of physiological sciences : JPS - 1 May 2013

Buroker Norman E, Ning Xue-Han, Zhou Zhao-Nian, Li Kui, Cen Wei-Jun, Wu Xiu-Feng, Zhu Wei-Zhong, Scott C Ronald, Chen Shi-Han

Abstract excerpt

Mountain sickness (MS) occurs among humans visiting or inhabiting high altitude environments. We conducted genetic analyses of seven single nucleotide polymorphisms (SNPs) in the promoter region of VEGFA gene for lowland (Han) and highland (Tibetan) Chinese. The seven SNPs were evaluated in Han and Tibetan patients with acute (A) and chronic (C) MS. We compared 64 patients with AMS with 64 Han unaffected with MS,...

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Identifiers

PMID: 23553563
DOI: 10.1007/s12576-013-0257-8
PMCID: PMC10717492

Genes

VEGFA

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