Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of CYB5A in Pancreatic Cancer Prognosis and Autophagy Modulation

3 Dec 2013

Abstract excerpt

BACKGROUND: Loss of 18q22.3 is a prognostic marker in pancreatic ductal adenocarcinoma (PDAC). This study investigated genes encoded by this cytoband. METHODS: We studied mRNA/protein expression in radically resected (n = 130) and metastatic patients (n = 50). The role of CYB5A was tested in 11 PDAC cell lines and five primary cultures through retrovirus-mediated upregulation and small interfering RNA using...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Cancer-related Molecular Pathways
Share to Protein Tyrosine Phosphatases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24301457
DOI: 10.1093/jnci/djt346

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of CYB5A in Pancreatic Cancer Prognosis and Autophagy ModulationPMID 24301457Read ↗

Identification and functional analysis of novel oncogene DDX60L in pancreatic ductal adenocarcinomaSemantic proximity Read ↗

A genetic variant conferred high expression of CAV2 promotes pancreatic cancer progression and associates with poor prognosis.Semantic proximity Read ↗

Inhibition of adipose tissue-derived fatty acid binding protein suppresses pancreatic cancer progression and metastasisSemantic proximity Read ↗

Dysregulated splicing factor SF3B1 unveils a dual therapeutic vulnerability to target pancreatic cancer cells and cancer stem cells with an anti-splicing drugSemantic proximity Read ↗

Bioinformatics analysis combined with experiments to explore potential prognostic factors for pancreatic cancerSemantic proximity Read ↗

COL6A1 promotes metastasis and predicts poor prognosis in patients with pancreatic cancerSemantic proximity Read ↗

Adipose-Tumor Crosstalk contributes to CXCL5 Mediated Immune Evasion in PDACSemantic proximity Read ↗

HOXB6 and HOXB8 control immune-cancer cell interactions in pancreatic cancerSemantic proximity Read ↗

B4GALT5 inhibits CD8+ T-cell response by downregulating MHC-I level through ERAD pathway in PDACSemantic proximity Read ↗

Functional role of BTB and CNC Homology 1 gene in pancreatic cancer and its association with survival in patients treated with gemcitabine.Semantic proximity Read ↗

WNT7B drives a program for pancreatic cancer subtype switching and progressionSemantic proximity Read ↗

BACH1 Promotes Pancreatic Cancer Metastasis by Repressing Epithelial Genes and Enhancing Epithelial–Mesenchymal TransitionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.