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Article

Blood-based gene expression signatures of medication-free outpatients with major depressive disorder: integrative genome-wide and candidate gene analyses.

Scientific reports - 5 Jan 2016

Hori Hiroaki, Sasayama Daimei, Teraishi Toshiya, Yamamoto Noriko, Nakamura Seiji, Ota Miho, Hattori Kotaro, Kim Yoshiharu, Higuchi Teruhiko, Kunugi Hiroshi

Abstract excerpt

Several microarray-based studies have investigated gene expression profiles in major depressive disorder (MDD), yet with highly variable findings. We examined blood-based genome-wide expression signatures of MDD, focusing on molecular pathways and networks underlying differentially expressed genes (DEGs) and behaviours of hypothesis-driven, evidence-based candidate genes for depression. Agilent human whole-genome...

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PMID: 26728011
DOI: 10.1038/srep18776
PMCID: PMC4700430

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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