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Article

Side Population Cells as Prototype of Chemoresistant, Tumor-Initiating Cells

1 Jan 2013

Abstract excerpt

Classically, isolation of CSCs from tumors exploits the detection of cell surface markers associated with normal stem cells. Invariable expression of these cell surface markers in almost all proliferating tumor cells that albeit impart specific functionality, the universality, and clinical credibility of CSC phenotype based on markers is still dubious. Side Population (SP) cells, as defined by Hoechst dye...

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Identifiers

PMID: 24294611
DOI: 10.1155/2013/517237

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