Article
Side populations of gastrointestinal cancers are not enriched in stem cells.
The Journal of pathology - 1 Apr 2008
Burkert J, Otto W R, Wright N A
Abstract excerpt
The side population (SP) phenotype, defined as the reserpine-blockable ability to efflux the nucleic acid dye Hoechst 33342, has been claimed to be enriched for stem cells in several human normal tissues, cancers and cell lines, and thus may be useful for the identification and isolation of cancer stem cells. We demonstrated the presence of SP fractions in all of seven tested gastrointestinal cancer cell lines....
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