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Side population cells isolated from human osteosarcoma are enriched with tumor‐initiating cells

8 Jul 2011

Abstract excerpt

It has been proven that "side population (SP)" cells that exclude Hoechst 33342 dye are enriched with cancer stem cells in several tumors. In the present study we aimed to isolate and characterize SP cells from human primary osteosarcoma. Side population cells were detected in osteosarcoma samples. In vitro, SP cells regenerated both SP and non-SP and the clonogenicity of SP cells was higher than that of non-SP...

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PMID: 21740477
DOI: 10.1111/j.1349-7006.2011.02028.x

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