Article
Human estrogen receptor (ER) gene promoter-P1: estradiol-independent activity and estradiol inducibility in ER+ and ER- cells.
Molecular endocrinology (Baltimore, Md.) - 1 Aug 1997
Treilleux, Peloux N, Brown M, Sergeant A
Abstract excerpt
Estrogen receptor (ER) is expressed at a low level in normal tissues such as breast and uterus but at a high level in breast and endometrial carcinomas. A proximal element (ERF-1) located between positions +133 and +204 relative to the promoter P1 major initiation site has been recently identifie...
Topics
- Baculoviridae
- Binding Sites
- Breast Neoplasms
- DNA-Binding Proteins
- Estradiol
- HeLa Cells
- Humans
- Mutation
- Promoter Regions, Genetic
- Receptors, Estrogen
- Transcription Factors
- Transfection
- Tumor Cells, Cultured