Article
Phenotypic and functional heterogeneity of CD169⁺ and CD163⁺ macrophages from porcine lymph nodes and spleen.
Developmental and comparative immunology - 1 May 2014
Alvarez Belén, Martínez Paloma, Yuste María, Poderoso Teresa, Alonso Fernando, Domínguez Javier, Ezquerra Angel, Revilla Concepción
Abstract excerpt
Secondary lymphoid organ macrophages are involved in the establishment of innate and acquired immunity. Here, we have isolated and characterized porcine lymph node and spleen CD169(+) and spleen CD163(+) macrophages. Lymph node and spleen CD169(+) macrophages can be both identified as CD172a(+)SLA-DR(hi)CD80/86(hi)CD14(int)TLR2(+)TLR4(+). On the other side, spleen CD163(+) macrophages are...
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