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Article

IL-22 contributes to TGF-β1-mediated epithelial-mesenchymal transition in asthmatic bronchial epithelial cells.

Respiratory research - 1 Nov 2013

Johnson Jill R, Nishioka Michiyoshi, Chakir Jamila, Risse Paul-André, Almaghlouth Ibrahim, Bazarbashi Ahmad N, Plante Sophie, Martin James G, Eidelman David, Hamid Qutayba

Abstract excerpt

BACKGROUND: Allergic asthma is characterized by airway inflammation in response to antigen exposure, leading to airway remodeling and lung dysfunction. Epithelial-mesenchymal transition (EMT) may play a role in airway remodeling through the acquisition of a mesenchymal phenotype in airway epithelial cells. TGF-β1 is known to promote EMT; however, other cytokines expressed in severe asthma with extensive...

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Identifiers

PMID: 24283210
DOI: 10.1186/1465-9921-14-118
PMCID: PMC4176096

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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