Article

Smad7 ameliorate small airway remodeling in COPD by modulating epithelial-mesenchymal transition

2024-05-30

Abstract excerpt

<title>Abstract</title> <p>Small airway remodeling is widely recognized as one of the major pathological changes 11 in chronic obstructive pulmonary disease (COPD), yet the underlying mechanisms remain 12 unclear. In the present study, we observed higher levels of epithelial-mesenchymal transition 13 (EMT) and increased collagen deposition in the lungs of both COPD patients and mice 14 models compared to the cont...

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Literature Corpus work: 7e051160-af1f-5e98-bdd7-12bd2b4bf043
DOI: 10.21203/rs.3.rs-4388824/v1

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