Article
Association study of the estrogen receptor I gene (ESR1) in anorexia nervosa and eating disorders: no replication found.
The International journal of eating disorders - 1 Mar 2014
Slof-Op 't Landt Margarita C T, van Furth Eric F, Meulenbelt Ingrid, Bartels Meike, Hottenga Jouke Jan, Slagboom P Eline, Boomsma Dorret I
Abstract excerpt
OBJECTIVE: The female preponderance and onset around puberty in the majority of eating disorders (EDs) suggest that sex hormones, like estrogens, may be involved in the onset of these disorders. An eight-SNP haplotype at the estrogen receptor I (ESR1) gene was found to be associated with anorexia nervosa (AN) (Versini et al., Neuropsychopharmacology, 35, 1818-1825, 2010) and three SNPs from this haplotype...
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