Association study of 182 candidate genes in anorexia nervosa.

doi:10.1002/ajmg.b.31082

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Article

Association study of 182 candidate genes in anorexia nervosa.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jul 2010

Pinheiro Andrea Poyastro, Bulik Cynthia M, Thornton Laura M, Sullivan Patrick F, Root Tammy L, Bloss Cinnamon S, Berrettini Wade H, Schork Nicholas J, Kaye Walter H, Bergen Andrew W, Magistretti Pierre, Brandt Harry, Crawford Steve, Crow Scott, Fichter Manfred M, Goldman David, Halmi Katherine A, Johnson Craig, Kaplan Allan S, Keel Pamela K, Klump Kelly L, La Via Maria, Mitchell James E, Strober Michael, Rotondo Alessandro, Treasure Janet, Woodside D Blake

Abstract excerpt

We performed association studies with 5,151 SNPs that were judged as likely candidate genetic variations conferring susceptibility to anorexia nervosa (AN) based on location under reported linkage peaks, previous results in the literature (182 candidate genes), brain expression, biological plausibility, and estrogen responsivity. We employed a case-control design that tested each SNP individually as well as...

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PMID: 20468064
DOI: 10.1002/ajmg.b.31082
PMCID: PMC2963154

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