Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Correlation of Chromosomal Instability, Telomere Length and Telomere Maintenance in Microsatellite Stable Rectal Cancer: A Molecular Subclass of Rectal Cancer

21 Nov 2013

Abstract excerpt

INTRODUCTION: Colorectal cancer (CRC) tumor DNA is characterized by chromosomal damage termed chromosomal instability (CIN) and excessively shortened telomeres. Up to 80% of CRC is microsatellite stable (MSS) and is historically considered to be chromosomally unstable (CIN+). However, tumor phenotyping depicts some MSS CRC with little or no genetic changes, thus being chromosomally stable (CIN-). MSS CIN- tumors...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Genetic factors in colorectal cancer
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24278232
DOI: 10.1371/journal.pone.0080015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Correlation of Chromosomal Instability, Telomere Length and Telomere Maintenance in Microsatellite Stable Rectal Cancer: A Molecular Subclass of Rectal CancerPMID 24278232Read ↗

Telomeres, telomerase and colorectal cancerSemantic proximity Read ↗

Relative telomere lengths in tumor and normal mucosa are related to disease progression and chromosome instability profiles in colorectal cancer.Semantic proximity Read ↗

Signatures of chromosomal instability in human cancersSemantic proximity Read ↗

Relationship between telomere shortening, genetic instability, and site of tumour origin in colorectal cancersSemantic proximity Read ↗

Relationship of telomere length in colorectal cancer patients with cancer phenotype and patient prognosisSemantic proximity Read ↗

The Landscape of Microsatellite Instability in Colorectal and Endometrial Cancer GenomesSemantic proximity Read ↗

Classification and characterization of microsatellite instability across 18 cancer types.Semantic proximity Read ↗

Chromosomal instability mediates immune exclusion and response to cytotoxic chemotherapy in colorectal liver metastasesSemantic proximity Read ↗

Telomere Length Maintenance and Its Transcriptional Regulation in Lynch Syndrome and Sporadic Colorectal CarcinomaSemantic proximity Read ↗

Genomic instability and colon cancer.Semantic proximity Read ↗

Microsatellite instability in colorectal cancer—the stable evidenceSemantic proximity Read ↗

Chr20q Amplification Defines a Distinct Molecular Subtype of Microsatellite Stable Colorectal Cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.