Association of cytokines, high sensitive C-reactive protein, VEGF and beta-defensin-1 gene polymorphisms and their protein expressions with chronic periodontitis in the Chinese population.

doi:10.5301/jbm.5000010

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Article

Association of cytokines, high sensitive C-reactive protein, VEGF and beta-defensin-1 gene polymorphisms and their protein expressions with chronic periodontitis in the Chinese population.

The International journal of biological markers - 23 Apr 2013

Tian Ye, Li Jin-le, Hao Liang, Yue Yuan, Wang Min, Loo Wings T Y, Cheung Mary N B, Chow Louis W C, Liu Qing, Yip Adrian Y S, Ng Elizabeth L Y, Chow Christopher Y C, Chow Christopher Y C

Abstract excerpt

PURPOSES: This study aimed at investigating the association between interleukin-6 (IL-6), interleukin-12 (IL-12), C-reactive protein (CRP), vascular endothelial growth factor (VEGF) and β-defensin-1polymorphisms and the susceptibility to periodontitis in the Chinese population. METHODS: DNA was extracted from the blood samples of 532 healthy individuals and 122 chronic periodontitis (CP) patients enrolled in the...

Topics

Adult
C-Reactive Protein
Case-Control Studies
China
Chronic Periodontitis
Female
Gene Frequency
Genetic Association Studies
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Interleukin-12

Interleukin-6

Male

Middle Aged

Polymorphism, Restriction Fragment Length

Polymorphism, Single Nucleotide

Vascular Endothelial Growth Factor A

beta-Defensins

Source

Open in PubMed

Identifiers

PMID: 23592000
DOI: 10.5301/jbm.5000010

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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