Article
Restoration of Bioactive Lantibiotic Suicin from a Remnant <i>lan</i> Locus of Pathogenic Streptococcus suis Serotype 2
23 Nov 2013
Abstract excerpt
Lantibiotics are ribosomally synthesized, posttranslationally modified antimicrobial peptides. Their biosynthesis genes are usually organized in gene clusters, which are mainly found in Gram-positive bacteria, including pathogenic streptococci. Three highly virulent Streptococcus suis serotype 2 strains (98HAH33, 05ZYH33, and SC84) have been shown to contain an 89K pathogenicity island. Here, on these islands, we...
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