Article
Glucagon-like peptide-1 (GLP-1) and its split products GLP-1(9-37) and GLP-1(28-37) stabilize atherosclerotic lesions in apoe⁻/⁻ mice.
Atherosclerosis - 1 Dec 2013
Burgmaier Mathias, Liberman Ana, Möllmann Julia, Kahles Florian, Reith Sebastian, Lebherz Corinna, Marx Nikolaus, Lehrke Michael
Abstract excerpt
BACKGROUND: [corrected] Glucagon-like peptide-1 (GLP-1) based therapies are new treatment options for patients with type 2 diabetes. Recent reports suggest vasoprotective actions of GLP-1. Similar beneficial effects might be reached by GLP-1(9-37) and the c-terminal GLP-1 split product (28-37) although both peptides do not activate the GLP-1 receptor. We therefore investigated the actions of GLP-1(7-37),...
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