Article

The Cardiovascular Physiology of Glucagon-like Peptide-1 Receptor Agonists: From Macro-level Outcomes to Micro-level Mechanisms

2025-07-17

Abstract excerpt

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have instigated a paradigm shift in the management of cardiometabolic disease. Initially developed for glycemic control in type 2 diabetes, their therapeutic role has expanded dramatically following the demon-stration of robust cardiovascular benefits in large-scale clinical trials. This review provides a comprehensive synthesis of the physiological mechanisms...

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Literature Corpus work: a1eb30ca-1b8e-599f-a4e2-0082f34a0ffd
DOI: 10.20944/preprints202507.1487.v1

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