Article
Pulmonary eosinophilia in mice devoid of interleukin-5.
Journal of leukocyte biology - 1 Jun 2002
Domachowske Joseph B, Bonville Cynthia A, Easton Andrew J, Rosenberg Helene F
Abstract excerpt
The biology of the eosinophilic leukocyte-development, recruitment, and prolonged existence in somatic tissues-has been linked almost invariably to the actions of the "eosinophil" cytokine, interleukin-5 (IL-5). Here we demonstrate that pulmonary eosinophilia can occur in the absence of IL-5, as morphologically normal eosinophils are recruited to the lungs of virus-infected IL-5 -/- mice with kinetics and...
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