Article
PPM1D mutations in circulating white blood cells and the risk for ovarian cancer.
Journal of the National Cancer Institute - 1 Jan 2014
Akbari Mohammad R, Lepage Pierre, Rosen Barry, McLaughlin John, Risch Harvey, Minden Mark, Narod Steven A
Abstract excerpt
We compared the frequency of PPM1D mutation in the white blood cells from 1295 ovarian cancer case patients and 834 control subjects. We found a truncating mutation in 20 case patients vs 1 control subject (odds ratio [OR] = 13.07; 95% confidence interval [CI] = 1.75 to 97.55; P < .001). The 12-y...
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