Article
[Contemporary pharmacogenetic approaches to the treatment of age-related macular degeneration].
Vestnik oftalmologii - 1 Jan 2000
Budzinskaia M V, Pogoda T V, Generozov E V, Chikun E A, Gurova I V, Shchegoleva I V, Sizova M V
Abstract excerpt
A study on the role of CFH, HTRA and IL-8 gene polymorphism in age-related macular degeneration (AMD) development has been conducted. At the first stage of the study genetic testing was done in 69 patients with exudative AMD and 370 random Moscow citizens without the disease. The goal of the second stage was to determine the influence of gene polymorphism on patient's response to endovitreal ranibizumab...
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