Article
The extra-cytoplasmic function sigma factor sigX modulates biofilm and virulence-related properties in Pseudomonas aeruginosa.
PloS one - 1 Jan 2013
Gicquel Gwendoline, Bouffartigues Emeline, Bains Manjeet, Oxaran Virginie, Rosay Thibaut, Lesouhaitier Olivier, Connil Nathalie, Bazire Alexis, Maillot Olivier, Bénard Magalie, Cornelis Pierre, Hancock Robert E W, Dufour Alain, Feuilloley Marc G J, Orange Nicole, Déziel Eric, Chevalier Sylvie
Abstract excerpt
SigX, one of the 19 extra-cytoplasmic function sigma factors of P. aeruginosa, was only known to be involved in transcription of the gene encoding the major outer membrane protein OprF. We conducted a comparative transcriptomic study between the wildtype H103 strain and its sigX mutant PAOSX, which revealed a total of 307 differentially expressed genes that differed by more than 2 fold. Most dysregulated genes...
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